Take the Waypoint to the Cavern of Wrath
Exit into the Cavern of Anger
Exit into the Merveil's Lair
Kill Merveil and enter the Southern Forest
Run through the zone and enter the Forest Encampment

Talk to Nessa to receive Poisonous Concoction
Talk to Nessa to buy Void Manipulation and Withering Step
Remove Weapon and buy shield (with movement speed implicit if possible)

(Optional): Find and complete the Labyrinth Trial
Find the exit to the Upper Prison
Find the exit to the Warden's Quarter's and head to the Warden's Chambers
Kill Brutus. Logout

Talk to Tarkleigh to receive Smoke Mine. Swap it with Dash

Take the Waypoint to the Prisoner's Gate
Exit into the Ship Graveyard
Grab the Waypoint. Find and enter the Ship Graveyard Cave
Retrieve the Allflame and exit back into the Ship Graveyard
Find the exit into the Cavern of Wrath and acquire the Waypoint
Take the Waypoint back to the Ship Graveyard
Talk to Fairgraves and kill him. Logout
Talk to Bestel and Tarkleigh to receive book of skill rewards

Talk to Nessa to receive Lesser Multiple Proj. Level it
Look for a better two-hand sword/axe

Take the Waypoint to the S. Passage. Find and enter the Flooded Depths
Find and kill the Deep Dweller. Logout
Take the Waypoint to the Submerged Passage
and find the entrance to the Ledge
Run through the Ledge. Enter the Climb
Run through the Climb
(Optional): Rescue Navali from the Faun
Enter the Lower Prison and grab the Waypoint. Return to town

Talk to Nessa to receive Quicksilver flask and Volley
Talk to Nessa to buy War Banner, Onslaught
Talk to Tarkleigh to receive Dash
Your current setup :

Enter the Coast and run to the end of the zone
Take the Waypoint and enter the Mud Flats
Find the 3 Rhoa Nests. Once you have them find the glyph wall and open the
exit to the Submerged Passage. Enter and grab the Waypoint
Move to the Coast and enter the Tidal Island
Find and kill Hailrake. Take Midecine Chest. Return to town

Look for G-G-R links and boots with movement speed
Take Splitting steel from Tarkleigh and equip it
Buy Two-Hand Sword from Tarkleigh and equip it

Kill Hillock at the end of the Twilight Strand
Enter the Lioneye's Watch

Lioneye's Watch (Act 1)

Basic info

This guide works for both 3.18 Sentinel and Standart leagues
If you are looking to level up in a new league as fast as possible but without
missing any of the essential quests, this guide is what you need
Some quests are not included, as they are simply not worth investing time
Helpful screenshots can be revealed by hovering over the colored text (FOR PC USERS ONLY)
except the blue one which is used to highlight NPC
Great league starter

Welcome to Poisonous concoction Pathfinder leveling guide (3.18)

Take the Waypoint to the Riverways. Find the exit into the Wetlands
Find Oak, kill him. Grab the amulet
Find the tree roots next to Waypoint, click on it, enter the Vaal Ruins
Break the seal when you encounter it. Exit into the Northern Forest
Run through the Northern Forest until you reach the exit into the Caverns
(Do not enter the Dread Thicket)
Grab the Waypoint and move to town, talk to Eramir to receive the Apex
Return to Caverns. Find and enter the Ancient Pyramid
Ascend the levels of the pyramid until you find the Pyramid Apex
Kill the Vaal Oversoul and exit into the City of Sarn
Find the Blackguards and kill them to rescue Clarissa. Talk to her
Enter the Sarn Encampment

Move to act1 and talk to Bestel to receive the book of skill reward

Enter the Riverways taking the left exit
Follow the road. Grab the waypoint. Keep going and enter the Western Forest
Grab the Waypoint and find the Blackguards. Kill them and click on
Thaumetic Seal to open the exit to Act I
Find and kill Alira. Grab the amulet
Find and enter the Weaver's Chambers. Make your way to the end
Enter the Weaver's Nest, kill the Weaver and take Maligaro's Spike. Logout

Talk to Greust to receive Herald of Agony
Talk to Yeena to buy Skitterbots, Blood Rage, Culling Strike

Take the right exit into the Old Fields
Follow the road until you find the exit into the Crossroads
Follow the road, find and grab the Waypoint
Take the right path to find the exit to the Broken Bridge
Follow the road until you find Kraityn. Kill him and grab the amulet. Logout
Take the Waypoint to the Crossroads
(Optional): Enter the Felshrine Ruins. Enter the Crypt
Find and complete the Labyrinth Trial. Logout
Take the Waypoint back to the Crossroads
Enter the Chamber of Sins(Lvl1). Exit into the Chamber of Sins(Lvl2)
(Optional): Find and complete the Labyrinth Trial
Find and kill Fidelitas. Take the Baleful Gem. Return to town

The forest encampment (Act 2)

Find and enter the Sceptre of God
Ascend the levels to find and enter the Upper Sceptre of God
Kill Dominus
Enter the Aqueduct and make your way through the area
Enter Highgate

Move to town. Enter the Aspirant's Plaza
Complete first labyrinth
Choose Pathfinder ascendancy. Skill Nature's Boon
Return to Imperial Gardens

Take the Waypoint to the Ebony Barracks
Find and enter the Imperial Gardens
(Optional): Find and complete the final Labyrinth Trial for the Normal Lab

Talk to Maramoa to receive Despair
Move to act1, talk to Nessa to buy Vitality (take +30 str node if needed)
Your setup :

Exit into the Slums
Find and enter the Crematorium
(Optional): Find and complete the Labyrinth Trial
Find Piety and kill her. Interact with Tolman
and take Tolman's Bracelet. Logout
Talk to Clarissa to receive the Sewer Keys
Enter the Slums and find the Sewer Grating. Open it and enter the Sewers
Find 3 Platinum Busts, grab the Waypoint. Find the exit into the Marketplace
((Optional): Grab the Waypoint and enter the Catacombs
Find and complete the Labyrinth Trial. Return to Marketplace via Waypoint)
Find the exit into the Battlefront
Find and grab the Waypoint and Lackguard Chest
Find and enter the Docks
Find the Supply Container and take Thaumetic Sulphite. Logout
Take the Waypoint to the Battlefront, find and enter the Solaris Temple
Run through the Solaris Temple (Level 1). Enter the Solaris Temple (Level 2)
Find and talk to Lady Dialla to receive the Infernal Talc (+ int amulet)
Take the Waypoint to the Sewers
Burn away the Undying Blockage. Enter the Ebony Barracks
Grab the Waypoint. Move through the area. Find and kill General Gravicius
Continue heading upwards. Enter the Lunaris Temple (Level 1)
Find and enter the Lunaris Temple (Level 2)
Find and kill Piety
Return to town. Talk to Grigor and Hargan to receive the book of skill rewards

The sarn encampment (Act 3)

Exit into the Ascent
Find the Resonator and take the Oriath Portal

Talk to Petarus and Vanja to buy Greater Volley
Talk to Dialla to receive Greater Multiple Projectiles
Move to act3, talk to Clarissa to buy Plague Bearer

Enter the Mines (Level 1) by using Deshret's Banner
Move through the area and enter the Mines (Level 2)
Find Deshret's Spirit and release it. Enter the Crystal Veins
Locate Dialla, grab the Waypoint. Enter Daresso's Dream
Move through the area, enter the Grand Arena
Find exit into the Ring of Blades
Kill Daresso and take Eye of Desire. Logout
Take the Waypoint to the Crystal Veins
Enter Kaom's Dream
Move through the area until you reach Kaom's Stronghold
Move through the area and enter the Caldera of the King.
Kill Kaom and take Eye of Fury. Logout
Talk to Tasuni to receive the book of skill
Take the Waypoint to the Crystal Veins. Talk to Dialla
Enter the Belly of the Beast (Level 1)
Move through the area, enter the Belly of the Beast (Level 2)
Move through the area, enter the Bowels of the Beast
Kill Piety. Talk to her, quit into the Harvest
Kill Malachai's 3 guardians: Doedre, Maligaro and Shavronne
Pick up the organs they drop
Enter the Black Core
Kill Malachai. Logout

Enter the Dried Lake
Move through the area and kill Voll , take Deshret's Banner. Logout

Highgate (Act 4)

Enter the Coast
Move through the area, find and enter the Mud Flats
Find and kill the Dishonored Queen and take Eye of Conquest
Find the exit into the Karui Fortress
Enter the Tukohama's Keep
Kill Tukohama
Find and enter the Ridge
Find and enter the Lower Prison
(Optional): Find and complete the Labyrinth Trial
Find and enter the Shavronne's Tower
Ascend the tower until you reach the Prison Rooftop
Kill Brutus and Shavronne. Logout
Take the Waypoint to the Prisoner's Gate
Move through the area. Enter the Valley of the Fire Drinker and kill Abberath
If you find the Western Forest first, enter it
you will do the Abberath quest later
Follow the main road and enter the Riverways
Follow the main road, grab the Waypoint
Find and enter the Wetlands
Move through the area and enter the Spawning Ground
Kill Puppet Mistress. Logout
(Take the Waypoint to the Prisoner's Gate, find the Valley of the Fire Drinker
and kill Abberath if you did not do it yet). Logout
Talk to Lilly, Bestel and Tarkleigh to receive the book of skill rewards
Take Waypoint to the Riverways. Find and enter the Southern Forest
Move through the area, enter the Cavern of Anger
Open the Flag Chest and take the Black Flag. Enter the passage
Move through the cavern until you reach the Beacon
Find the pyramid-esque structure and ascend it
Escort the two pillars to their berths by standing within the glowing circle
Click on the ignition switch and then again on the Beacon
Talk to Weylam and sail to the Brine King's Reef
Find and enter the Brine King's Throne
Kill Brine King
Talk to Weylam and sail to Act 7

Talk to Lilly to buy Second Wind and Grace. Remove Vitality
Your setup :

Talk to Lilly to take the Twilight Strand quest. Enter the Twilight Strand
Clear the area. Return to town

Lioneye's Watch(Act 6)

Enter the Broken Bridge
(Optional): Find Silver Locket and deliver it to Weylam
Enter the Crossroads
Follow the road, grab the Waypoint and enter the Fellshrine Ruins
Move through the area and enter the Crypt
(Optional): Find the Labyrinth Trial and complete it
Find the Sarcophagus and descend to the Crypt(Level2)
Find the Container of Sins and take Maligaro's Map. Logout
Talk to Weylam and take Diamond Flask as a reward. Equip it
Take the Waypoint to the Crossroads
Enter the Chamber of Sins (Lvl1)
Find the map device and insert Maligaro's Map into it
Enter Maligaro's Sanctum and find Maligaro's Workshop
Kill Maligaro and take Black Venom. Leave the map via portal scroll
Talk to Silk and take the Obsidian Key
Find and enter the Chamber of Sins (Lvl2)
(Optional): Find and complete the final Labyrinth Trial for the Cruel Lab
Find and enter the Den
Move through the Ashen Fields and quit into the Fortress Encampment
Kill Greust. Quit into the Northern Forest
Move through the area and find the Dread Thicket. Make a portal near it and move on until you find the Causeway. Enter it
Move through the area. Find Kishara's Star and enter the Vaal City
Find Yeena and grab the Waypoint
Return to the Bridge Encampment via Waypoint and enter the portal
Enter the Dread Thicket
Collect 7 Fireflies from around the Dread Thicket
Find and enter the Den of Despair and kill Gruthkul. Logout
Talk to Weylam and Eramir to receive the book of skill rewards
Take the Waypoint to the Vaal City
Talk to Yeena and enter the Temple of Decay (Level 1)
Find and Enter the Temple of Decay (Level 2)
Find and Enter the Arakaali's Web
Kill Arakaali. Quit into the Sarn Ramparts
Move through the area and enter the Sarn Encampment(act8)

The Bridge Encampment(Act 7)

Enter the Toxic Conduits
Find and enter the Doedre's Cesspool
Open the grate and enter the Cauldron
Kill Doedre the Vile
Exit into the Toxic Conduits and grab the Waypoint
Take the right path and enter the Quay
Find the Sealed Casket and take the Ankh of Eternity
Find and enter the Ressurection Site and talk to Clarissa
Kill Tolman. Return to the Quay
Enter the Grain Gate
Kill the Gemling Legionnaires
Enter the Imperial Fields
Move through the area and enter the Solaris Temple(Lvl1)
Find and grab the Waypoint
Find and enter the Solaris Temple(Lvl2)
Kill Dawn and take Sun Orb. Logout
Take the Waypoint to the Solaris Temple (Lvl1)
Find and enter the Solaris Concourse
Enter the Harbour Bridge
Move through the area, past Sky Shrine until
you encounter Lunaris Concourse, enter it
Move through the area, enter the Lunaris Temple (Lvl1)
Enter the Lunaris Temple (Lvl2)
Kill Dusk and take Moon Orb. Logout
Take the Waypoint to the Lunaris Concourse. Enter the Harbour Bridge
Move through the area and enter the Sky Shrine
Kill Solaris and Lunaris
Enter the Blood Aqueducts
Enter the Highgate
Return to Toxic Conduits(previous act) via Waypoint
Take the left path and enter the Grand Promenade
Enter the Bath House. Grab the Waypoint
(Optional): Find and complete the Labyrinth Trial
Enter the High Gardens and run until you encounter the Pools of Terror
Enter and kill Yugul. Logout
Talk to Maramoa, Hargan and Clarissa to receive the book of skill rewards
Return to Highgate(act9)

The Sarn Encampment(Act8)

Enter the Aspirant's Plaza. Complete second labyrinth
Skill Nature's Reprisal. Return to town

Enter the Descent
Descend via the Supply Hosts until you locate the exit into the Vastiri Desert
Find and grab the Waypoint
Find the Storm Weathered Chest
Defeat the waves of mummies that ambush you, then take the Storm Blade
Find the entrance to the Oasis
Return to town via portal scroll
Talk to Sin. Talk to Petarus and Vanja and take Bottled Storm
Use portal to return to Vastiri Desert
Enter the Oasis
Find and enter the Sand Pit
Kill Shakari and return to Highgate
Take the Waypoint to the Vastiri Desert. Find and enter the Foothills
Grab the waypoint and enter the Boiling Lake
Move through the area and Kill Basilisk and take Basilisk Acid. Logout
Return to Foothills via Waypoint
Find and enter the Tunnel
(Optional): Find and complete the Labyrinth Trial
Enter the Quarry
Move straight to the middle of the zone and grab the Waypoint
( If refinery is on the right side - Shrine of the Winds is on the left one
If you see Shrine of the winds on right side - Refinery is on top of the area )
Enter the Refinery and explore the area until you find and kill General Adus
Take Trarthan Powder. Logout
Return to Quarry via Waypoint
Enter the Shrine of the Winds and kill Garukhan. Take Sekhema Feather
Return to town. Talk to Irasha and Tasuni to receive the book of skill rewards
Return to Quarry via Waypoint
Talk to Sin and enter the Belly of the Beast
Enter the Rotting Core and make your way through the area
Enter the Black Core and talk to Sin
Enter each of the portals in your order of choosing and defeat Malachai's guardians ( Shavronne, Maligaro and Doedre)
Enter the Black Heart and kill Depraved Trinity
Talk to Lilly and sail to Oriath

Highgate(act9)

Enter the Cathedral Rooftop
Enter the Cathedral Apex
Kill the Cultists and Gargoyles to free Bannon
Return to the Cathedral Rooftop and make your way to the right
Enter the Ravaged Square
Create portal, grab the Ravaged Square Waypoint
Move to the Torched Courts
Run through the area, enter the Desecrated Chambers
Run through the area, enter the Sanctum of Innocence
Kill Avarius Reassembled. Quit to the Desecrated Chambers
Return to the Oriath Docks via Waypoint
Enter the portal you have created earlier
Enter the Control Blocks. Move through the area and kill Vilenta. Logout
((optional): Take the Waypoint to the Ravaged Square
Enter the Ossuary and Elixir of Allure
Find and complete the final Labyrinth Trial for the Merciless Lab. Logout )
Talk to Lani to receive the book of skill reward
Talk to Innocence

Take the Waypoint to the Aspirant's Plaza. Complete third labyrinth
Skill Master Toxicist. Return to Oriath Docks

Take the Waypoint to the Ravaged Square. Talk to Innocence
Enter the Canals and move through the area
Enter the Feeding Trough and move through the area
Talk to Sin and enter the Altar of Hunger
Kill Kitava
Talk to Lani in Oriath to receive the Book of Skill reward

Oriath Docks(Act10)