Would recommend to buy second
Life Flask for this purpose
Take
Vile Bastion
Here you can find current UberLab scheme
Helmet enchant : 'Despair has increased Curse effect / Poison Multi while infecting'
If expensive - use random wand with DoT crafted until you can afford it
If you use shield - use life essence on Int shield base and craft resistance
Life Flask with instant life recovery and bleed immunity
Quicksilver Flask (movement speed)
There are 2 Movement Speed flasks which are good for us :
Silver Flask with reduced effect of curses
I would not recommend to roll it with alts, better to buy it
Jade Flask with Immunity to Freeze and Chill
Buy a base. Use Life essence until you get any resistance and have an empty suffix. When your poison on hit chance is high enough - add a crafted mod 'increased duration of ailments while focused' . Despair effect enchantment might be expensive at league start, buy Poison Multi while Infecting if poor! (check the filter)
Anointment - Toxic Strikes
(Clear+Amber+Crimson)
You can buy a base and use Chaos Reforge in Harvest to make it cheaper
Roll until you get at least 2 decent notables
*Items and colored Text contain promts on hover and links on click
Soul of Lunaris : Put the Moon Temple Map and Divine Vessel into the Map Device and run the map. Right Click on the vessel to unlock the bonus
Repeat with
Forbidden Woods Map for the next Tier
Repeat with
Cold River Map for the next Tier
Soul of Yugul : Put the Grave Trough and Divine Vessel into the Map Device and run the map
Right Click on the vessel to unlock the bonus
Pantheon : Soul of Lunaris + Soul of Shakari
You should have ~50 str in summary on your gear, one good roll on a ring would be enough
DoT Multi + enchantment when you turn to poison
Rings and Amulet should have an empty prefix to craft minus manacost. You want at least 1 mod for 6-Link when switch to Impending Doom
You want Chaos DoT Multi / DoT Multi for dps, if you are missing stats/res - take them instead
How it works :
You want to rewrite your curses to proc Impending Doom. One is being self cast (Temporal Chains)
The rest curses should be socketed into the gloves
Put Punishment in the first socket and then the curses you want to being applied, plus spell cascade. The Curse from the first socket won't be applied
Make sure to have
this for 100% poison on hit chance :
If you do not have medium cluster with Septic Spells or Toxic Strikes Enchantment on an amulet yet - take 20% chance to poison Cursed enemies (Curse Mastery)
When you equip gloves - remove Cursed Ground from Temp Chains and add Added Chaos Damage
This setup would allow you to kill Exarch/Eater bosses and farm T16 maps
You can find complete red map viable setup with a couple additions below
You should keep in mind that Expedition Encounters may contain 'Immune to Curses' mod which makes mobs completely invulnerable to our damage. This mod is not being highlighted and can hardly be noticed while placing explosives (ty ggg). To solve this we equip any 4-6 link weapon in off hand and use Soulrend setup we had been using before
I would recommend to switch to Impending Doom when Uber Lab is completed
If you switched to Impending Doom, still have Uber Lab not completed and feel like clear speed isn't great - take Profane Bloom instead of Vile Bastion
If expensive - remove Brush with Death from the filter
To figure out what maps you have to run to complete the pantheon - open atlas and enter it's name
Every league maps are different
You can use Soul of the Brine King for Freeze Immune if needed while you have no ele ailment avoidance
While you have Apep's Rage and a shield you should insert Wither and Malevolence into them so when you switch to kill expedition monsters you wouldn't lose auras
If you want to have a Shield Charge - remove Wither totem and use Withering Step instead
Small cluster jewel with Enduring Composure
Endurance charge generation for 90% physical damage reduction
If you are bad at making currency or Vixen's price fly to the moon - ignore it until the price is affordable for you
Keep using Cursed Ground and cast Despair manually
If you have ES issues - remove Witherning Presence and take Vile Bastion until Uber lab
Craft reduced manacost on a flask (use TFT to buy)
Craft minus non chann manacost on jewelry